Description

6,8-Dichloro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetically derived organic compound that serves as a critical building block in advanced pharmaceutical research and development. This heterocyclic amine salt is valued for its role as a versatile synthetic intermediate, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of novel therapeutic agents targeting central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those with isoquinoline or tetrahydroisoquinoline scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new active pharmaceutical ingredients (APIs).
• Chemical Synthesis: Serves as a versatile building block for creating libraries of compounds in combinatorial chemistry for high-throughput screening.
• Academic Research: Employed in universities and research institutes for studying heterocyclic chemistry, reaction mechanisms, and developing new synthetic methodologies.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and pesticides.

Basic Information

Product Name	6,8-Dichloro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	73075-50-0
Molecular Formula	C9H9Cl2N • HCl
Molecular Weight	252.55 g/mol
Synonyms	6,8-Dichloro-1,2,3,4-tetrahydroisoquinoline HCl; 6,8-Dichloro-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-6,8-dichloroisoquinoline hydrochloride; 6,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline monohydrochloride; 6,8-Dichlorotetrahydroisoquinoline hydrochloride; 73075-50-0; 6,8-Dichloro-THIQ HCl
EINECS	Contact for details

Quality Control

Our 6,8-Dichloro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.