Description

5-Chloro-1,2,3,4-Tetrahydroisoquinoline is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core structure serves as a privileged scaffold for developing pharmacologically active molecules, making it a critical intermediate for research and development. This compound is primarily utilized by pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of central nervous system (CNS) active compounds, potential antidepressants, and neuroprotective agents.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators with specific biological activity.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating organic semiconductors, conductive polymers, and advanced functional materials.
• Chemical Biology Probes: Serves as a core structure for designing fluorescent tags, enzyme inhibitors, and molecular probes for biological studies.
• Academic & Contract Research: Essential reagent for methodological development, library synthesis, and discovery chemistry in R&D laboratories.

Basic Information

Product Name	5-Chloro-1,2,3,4-Tetrahydroisoquinoline
CAS No.	73075-43-1
Molecular Formula	C9H10ClN
Molecular Weight	167.63 g/mol
Synonyms	5-Chloro-1,2,3,4-tetrahydroisoquinoline; 5-Chloro-THIQ; 5-Chloro-3,4-dihydroisoquinoline; 5-Chloro-1,2,3,4-tetrahydro-isoquinoline; 5-Chloroisoquinoline, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydro-5-chloroisoquinoline; 5-Chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,2,3,4-Tetrahydroisoquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.