Description

8-Chloro-4-Methyl-1,2,3,4-Tetrahydroisoquinoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Ligand and Catalyst Synthesis: Serves as a building block for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A monomer or precursor for advanced polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bio-conjugates for studying biological processes.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in research laboratories.

Basic Information

Product Name	8-Chloro-4-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	73037-84-0
Molecular Formula	C10H12ClN
Molecular Weight	181.66 g/mol
Synonyms	8-Chloro-4-methyl-1,2,3,4-tetrahydroisoquinoline; 4-Methyl-8-chloro-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-8-chloro-4-methylisoquinoline; 8-Chloro-4-methyl-THIQ; 73037-84-0; 8-Chloro-4-methyl-1,2,3,4-tetrahydro-isoquinoline
EINECS	Contact for details

Quality Control

Our 8-Chloro-4-Methyl-1,2,3,4-Tetrahydroisoquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.