Description

Methyl Chloroacetate, [1-14C] is a carbon-14 radiolabeled derivative of methyl chloroacetate, a key chemical intermediate. This isotopically labeled compound is essential for conducting precise metabolic and environmental fate studies, providing critical data on molecular pathways and degradation. It is primarily utilized by researchers and scientists in the pharmaceutical, agrochemical, and environmental science sectors for advanced tracer applications and analytical method development.

Application

• Tracer Studies in Pharmaceutical Research: Used to investigate the metabolic pathways, absorption, distribution, and excretion (ADME) of new drug candidates and their metabolites.
• Agrochemical Metabolism and Degradation Analysis: Essential for studying the environmental fate, metabolic breakdown, and residue profiling of pesticides and herbicides.
• Biochemical Pathway Elucidation: Serves as a labeled precursor in the synthesis of more complex radiolabeled compounds for probing specific biochemical mechanisms.
• Analytical Method Development and Validation: Employed as a reference standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and other analytical techniques to ensure accuracy and sensitivity.
• Environmental Science Research: Applied in studies tracking the degradation and transformation of chemical pollutants in various ecosystems.

Basic Information

Product Name	Methyl Chloroacetate, [1-14C]
CAS No.	73000-55-2
Molecular Formula	C3H5Cl14COOCH3 or C3H5ClO2 (14C at C-1)
Molecular Weight	~108.52 (based on 12C formula, exact mass varies with 14C enrichment)
Synonyms	Methyl 2-chloroacetate-1-14C; Chloroacetic acid methyl ester-1-14C; Methyl chloroacetate-1-carbon-14; [1-14C]Methyl chloroacetate; Methyl monochloroacetate-1-14C; Methyl chloromethanoate-1-14C; MCA-1-14C; Methyl ester of chloroacetic acid-1-14C
EINECS	Contact for details

Quality Control

Every batch of our Methyl Chloroacetate, [1-14C] is manufactured and analyzed under strict quality systems to ensure high chemical and radiochemical purity, meeting the exacting requirements of research applications. Comprehensive Certificates of Analysis (COA) are provided, detailing parameters such as radiochemical purity, specific activity, and chemical identity. Our quality commitment aligns with GLP (Good Laboratory Practice) principles to support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, well-ventilated area for radioactive materials. Keep away from strong acids and organic solvents. Adhere to all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Customizable (mCi/mmol)
Solvent	As specified (e.g., Toluene, Acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.