Description

4-Bromobicyclo[2.2.2]octan-1-ol is a specialized brominated bicyclic alcohol building block of significant interest in advanced organic synthesis. This compound matters for its rigid, three-dimensional structure, which serves as a key intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, catalysts, and functional materials where a sterically defined scaffold is required.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with unique modes of action.
• Ligand and Catalyst Synthesis: Acts as a precursor for creating sterically hindered ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the synthesis of monomers for specialty polymers with enhanced thermal and mechanical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including novel coupling and functionalization reactions.

Basic Information

Product Name	4-Bromobicyclo[2.2.2]octan-1-ol
CAS No.	72948-88-0
Molecular Formula	C8H13BrO
Molecular Weight	205.09 g/mol
Synonyms	1-Bromo-4-hydroxybicyclo[2.2.2]octane; 4-Bromo-1-hydroxybicyclo[2.2.2]octane; Bicyclo[2.2.2]octan-1-ol, 4-bromo-; 4-Bromobicyclo[2.2.2]octanol; 1-Hydroxy-4-bromobicyclo[2.2.2]octane; 4-Bromo-1-bicyclo[2.2.2]octanol
EINECS	Contact for details

Quality Control

Our 4-Bromobicyclo[2.2.2]octan-1-ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to reliable supply and traceable documentation supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.