Description

2-Bromo-4-(Trifluoromethyl)Thiazole-5-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic combination of a reactive bromine atom and a stable trifluoromethyl group on the thiazole scaffold, enabling precise molecular modifications. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in antiviral, antibacterial, and anticancer research programs.
• Agrochemical Synthesis: Used in the construction of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized molecules used in organic electronics and specialty polymers.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Thiazole-5-Carboxylic Acid Ethyl Ester
CAS No.	72850-79-4
Molecular Formula	C7H5BrF3NO2S
Molecular Weight	304.09 g/mol
Synonyms	Ethyl 2-Bromo-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate; 2-Bromo-4-(trifluoromethyl)-5-thiazolecarboxylic Acid Ethyl Ester; 5-Carbethoxy-2-bromo-4-trifluoromethylthiazole; 72850-79-4; 2-Bromo-4-trifluoromethylthiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Thiazole-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.