Description

2-Chloro-4-(1,1-Dimethylethyl)-5-Thiazolecarboxylic Acid Ethyl Ester is a high-value, synthetically versatile thiazole derivative. This compound serves as a critical advanced pharmaceutical intermediate and a key building block in the synthesis of complex organic molecules. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, photoactive materials, and polymers with tailored electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new chemical reactions and synthesizing novel heterocyclic compounds for screening libraries.

Basic Information

Product Name	2-Chloro-4-(1,1-Dimethylethyl)-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	72850-77-2
Molecular Formula	C10H14ClNO2S
Molecular Weight	247.74 g/mol
Synonyms	Ethyl 2-Chloro-4-tert-butylthiazole-5-carboxylate; 2-Chloro-4-tert-butyl-5-thiazolecarboxylic Acid Ethyl Ester; 5-Thiazolecarboxylic acid, 2-chloro-4-(1,1-dimethylethyl)-, ethyl ester; Ethyl 2-chloro-4-(tert-butyl)thiazole-5-carboxylate; 72850-77-2; 2-Chloro-4-tert-butylthiazole-5-carboxylic acid ethyl ester; 4-tert-Butyl-2-chlorothiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(1,1-Dimethylethyl)-5-Thiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and batch-to-batch consistency suitable for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.