Description

3-(Piperidin-4-Yl)Indolin-2-One is a high-purity, advanced pharmaceutical intermediate featuring a fused indolinone and piperidine scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules targeting central nervous system and oncological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for neurological disorders and cancer.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective kinase inhibitors and receptor modulators.
• Neurological Research: Serves as a core scaffold for developing novel compounds targeting serotonin and dopamine receptors for potential antidepressant or antipsychotic applications.
• Oncology Drug Discovery: Utilized in constructing candidate molecules for targeted cancer therapies due to its privileged structure.
• Chemical Biology: Used as a probe or tool compound in biochemical assays to study specific enzyme interactions and signaling pathways.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: Acts as a starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	3-(Piperidin-4-Yl)Indolin-2-One
CAS No.	72831-89-1
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	3-(4-Piperidinyl)-1,3-dihydro-2H-indol-2-one; 3-(Piperidin-4-yl)indolin-2-one; 2-Indolinone, 3-(4-piperidinyl)-; 3-(1,2,3,6-Tetrahydro-4-pyridinyl)-1,3-dihydro-2H-indol-2-one; 3-(4-Piperidyl)indolin-2-one; 72831-89-1; 3-Piperidin-4-yl-indolin-2-one
EINECS	Contact for details

Quality Control

Our 3-(Piperidin-4-Yl)Indolin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.