Description

7,8-Epoxydihydrocodeinone is a key pharmaceutical intermediate and a structurally significant derivative of thebaine. This compound is valued for its role in the synthesis of potent opioid analgesics and other specialized active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in advanced narcotic and pain management drug development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of high-potency opioid analgesics such as oxycodone and related compounds.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new analgesic agents.
• Reference Standard: Serves as an analytical standard in quality control laboratories for the identification and quantification of related substances.
• Controlled Substance Synthesis: Employed under strict regulatory oversight for the licensed production of Schedule II narcotics.
• Academic Research: Utilized in university and institutional labs for pharmacological studies on opioid receptor interactions.

Basic Information

Product Name	7,8-Epoxydihydrocodeinone
CAS No.	72785-19-4
Molecular Formula	C18H19NO4
Molecular Weight	313.35 g/mol
Synonyms	14-Hydroxycodeinone; Thebaine-7,8-epoxide; 7,8-Dihydro-14-hydroxycodeinone; 4,5α-Epoxy-3-hydroxy-14-methoxy-17-methylmorphinan-6-one; 14-Hydroxy-7,8-dihydrocodeinone; 7,8-Epoxy-14-hydroxydihydrocodeinone
EINECS	Contact for details

Quality Control

Our 7,8-Epoxydihydrocodeinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identification by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.