Description

Ethyl 2-[(Tricyclo[3.3.1.1~3,7~]Dec-1-Ylcarbonyl)Amino]-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex polycyclic adamantane-derived structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for CNS-targeting molecules.
• Organic Synthesis Research: Used in academic and industrial research to explore new chemical entities and reaction pathways involving adamantane and tetrahydrobenzothiophene motifs.
• Protease Inhibitor Development: Serves as a precursor in the research and development of protease inhibitors due to its specific steric and electronic properties.
• Ligand Synthesis: Employed in the creation of specialized ligands for medicinal chemistry and catalyst design.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Ethyl 2-[(Tricyclo[3.3.1.1~3,7~]Dec-1-Ylcarbonyl)Amino]-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate
CAS No.	72625-09-3
Molecular Formula	C22H27NO3S
Molecular Weight	385.52 g/mol
Synonyms	Ethyl 2-[(1-Adamantanecarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-[(Tricyclo[3.3.1.1~3,7~]dec-1-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester; 1-Adamantanecarboxamide, N-(3-(ethoxycarbonyl)-4,5,6,7-tetrahydro-1-benzothien-2-yl)-; UNII-7K2B4VJ3F1; 7K2B4VJ3F1; Ethyl 2-(adamantane-1-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-[(Tricyclo[3.3.1.1~3,7~]Dec-1-Ylcarbonyl)Amino]-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.