Description

Ethyl 2-((4-Nitrophenyl)Carbonylamino)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is a high-purity synthetic organic compound featuring a tetrahydrobenzo[b]thiophene core, a key structural motif in advanced chemical synthesis. This compound is valued for its role as a versatile pharmaceutical intermediate and a critical building block in the development of novel active ingredients. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for process development and scale-up activities.

Application

This specialized intermediate is designed for high-value synthesis applications where precise molecular architecture is required. Its primary and potential uses include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Research: Serves as a building block for developing new active ingredients for crop protection products, such as herbicides or fungicides.
• Chemical Synthesis: Used in organic chemistry research for constructing complex heterocyclic systems and for method development in catalysis.
• Material Science Precursor: Potential application in the synthesis of organic electronic materials or specialty dyes due to its conjugated thiophene structure.

Basic Information

Product Name	Ethyl 2-((4-Nitrophenyl)Carbonylamino)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate
CAS No.	72625-08-2
Molecular Formula	C18H18N2O5S
Molecular Weight	374.41 g/mol
Synonyms	Ethyl 2-[(4-nitrobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 4,5,6,7-Tetrahydrobenzo[b]thiophene-3-carboxylic acid, 2-[[(4-nitrophenyl)carbonyl]amino]-, ethyl ester; 2-((4-Nitrobenzoyl)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester; Ethyl 2-(4-nitrobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; 72625-08-2; 4,5,6,7-Tetrahydro-2-[(4-nitrobenzoyl)amino]benzo[b]thiophene-3-carboxylic Acid Ethyl Ester.
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-((4-Nitrophenyl)Carbonylamino)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. All materials are manufactured under a cGMP-compliant quality management system. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as verified by advanced analytical techniques including HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.