Description

Ethyl 2-(3,4,5-Trimethoxybenzamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• API Synthesis: A key building block for the production of complex molecules targeting specific biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological research projects.
• Process Chemistry: Employed in the development and scale-up of efficient synthetic routes for new therapeutics.

Basic Information

Product Name	Ethyl 2-(3,4,5-Trimethoxybenzamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate
CAS No.	72625-07-1
Molecular Formula	C21H25NO6S
Molecular Weight	419.49 g/mol
Synonyms	Ethyl 2-[(3,4,5-trimethoxybenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 4,5,6,7-Tetrahydro-2-[[(3,4,5-trimethoxyphenyl)carbonyl]amino]benzo[b]thiophene-3-carboxylic Acid Ethyl Ester; 2-(3,4,5-Trimethoxybenzoylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic Acid Ethyl Ester; Benzo[b]thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(3,4,5-trimethoxyphenyl)carbonyl]amino]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3,4,5-Trimethoxybenzamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.