Description

Isopropyl2-(1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1H-Indol-3-Yl)Acetate is a high-purity synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly within the non-steroidal anti-inflammatory drug (NSAID) class. It is essential for R&D chemists and process development teams in the pharmaceutical and fine chemical industries seeking reliable, high-quality raw materials for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of indole-based active pharmaceutical ingredients (APIs).
• Non-Steroidal Anti-Inflammatory Drug (NSAID) Research: Central to the development and process optimization of new anti-inflammatory and analgesic compounds.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Process Chemistry & Scale-Up: Employed in pilot plant and commercial-scale manufacturing of specialized pharmaceuticals.
• Reference Standard: Serves as an analytical standard for quality control and regulatory submissions in API production.
• Custom Synthesis: A starting material for the contract manufacturing of complex, proprietary molecules for the life sciences sector.

Basic Information

Product Name	Isopropyl2-(1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1H-Indol-3-Yl)Acetate
CAS No.	72616-25-2
Molecular Formula	C22H22ClNO4
Molecular Weight	399.87 g/mol
Synonyms	Isopropyl [2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]]acetate; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-(2-isopropoxy-2-oxoethyl)-1H-indole; 2-(1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1H-Indol-3-Yl)Acetic Acid Isopropyl Ester; Indomethacin Isopropyl Ester Derivative; Isopropyl 2-(1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl)acetate
EINECS	Contact for details

Quality Control

Our Isopropyl2-(1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1H-Indol-3-Yl)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines and can provide material meeting specifications for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; store away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.