Description

Isosilybin is a specific, bioactive flavonolignan isomer derived from the milk thistle plant (*Silybum marianum*). This compound matters for its targeted biological activity and high purity, which are critical for advanced research and product development. It is primarily needed by manufacturers in the nutraceutical, pharmaceutical, and cosmeceutical industries seeking standardized, high-quality botanical extracts for health and wellness applications.

Application

• Dietary Supplement Formulation: A key active ingredient in premium liver support and antioxidant nutraceutical products.
• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) in studies targeting liver health, metabolic syndrome, and oncology.
• Cosmeceutical Products: Incorporated into anti-aging and skin-protective formulations for its antioxidant and anti-inflammatory properties.
• Functional Food & Beverages: An additive for health-enhancing drinks and food products requiring a standardized silymarin complex component.
• Analytical Reference Standard: Serves as a high-purity certified standard for HPLC and LC-MS analysis in quality control and research laboratories.
• Veterinary Health Products: Used in supplements designed to support liver function in companion and production animals.

Basic Information

Product Name	Isosilybin
CAS No.	72581-71-6
Molecular Formula	C25H22O10
Molecular Weight	482.44 g/mol
Synonyms	Isosilybin A/B (mixture); 2,3-Dehydrosilybin; 3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-4-chromanone; Silybin B; Isosilibinin; Milk Thistle Isomer; Flavonolignan from *Silybum marianum*
EINECS	Contact for details

Quality Control

Our Isosilybin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is tested using advanced analytical techniques, including HPLC and MS, to verify identity, potency, and the absence of harmful contaminants. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP, ISO, and relevant pharmacopeial guidelines for botanical extracts.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥95% (Total Isosilybin A & B)
Loss on Drying	≤2.0%
Residue on Ignition	≤1.0%
Heavy Metals (as Pb)	≤10 ppm
Residual Solvents	Meets ICH guidelines
Microbial Limits	Meets USP/EP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.