Description

3-Amino-5-Chloroindole is a high-value indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both amino and chloro substituents, makes it a versatile building block for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors and serotonin receptor modulators.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the creation of organic semiconductors, dyes, and photochromic materials.
• Biochemical Research: Serves as a scaffold for designing enzyme inhibitors and fluorescent probes.
• Organic Synthesis: Versatile starting material for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and ring-forming reactions.

Basic Information

Product Name	3-Amino-5-Chloroindole
CAS No.	72561-51-4
Molecular Formula	C8H7ClN2
Molecular Weight	166.61 g/mol
Synonyms	5-Chloro-1H-indol-3-amine; 5-Chloro-3-indolamine; 5-Chloroindol-3-ylamine; 3-Amino-5-chloro-1H-indole; 5-Chloro-3-aminoindole; 1H-Indol-3-amine, 5-chloro-; 3-Amino-5-chloroindole; 5-Chloro-1H-indol-3-amine
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Chloroindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder/crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.