Description

2-Oxa-5-Azabicyclo[2.2.1]Heptan-3-One, 5-Acetyl-, (1S)- (9Ci) is a high-purity chiral bicyclic lactam derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. Its value lies in its rigid, functionalized structure which is essential for constructing complex molecules with high stereochemical fidelity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug molecules, particularly in neurological and anti-infective therapeutic areas.
• Asymmetric Synthesis: Acts as a versatile building block for constructing stereochemically defined heterocycles and fused ring systems.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high stereochemical control.

Basic Information

Product Name	2-Oxa-5-Azabicyclo[2.2.1]Heptan-3-One, 5-Acetyl-, (1S)- (9Ci)
CAS No.	72485-25-7
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	(1S)-5-Acetyl-2-oxa-5-azabicyclo[2.2.1]heptan-3-one; (1S,4R)-5-Acetyl-2-oxa-5-azabicyclo[2.2.1]heptan-3-one; 5-Acetyl-2-oxa-5-azabicyclo[2.2.1]heptan-3-one, (1S)-; (1S)-5-Acetyl-2-oxa-5-azabicyclo[2.2.1]heptan-3-one (9CI); 72485-25-7; (1S,4R)-rel-5-Acetyl-2-oxa-5-azabicyclo[2.2.1]heptan-3-one; Chiral bicyclic lactam derivative
EINECS	Contact for details

Quality Control

Our 2-Oxa-5-Azabicyclo[2.2.1]Heptan-3-One, 5-Acetyl-, (1S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.