Description

Praeruptorin E CAS NO 72463-77-5 is a high-purity, naturally occurring pyranocoumarin compound isolated from *Peucedanum praeruptorum* and related species. This compound is of significant interest for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate in research and development. It is primarily sought by professionals in the pharmaceutical, biotechnology, and nutraceutical industries for applications in cardiovascular research, anti-inflammatory studies, and metabolic disorder investigations.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished products in quality control laboratories.
• Bioactive Compound Research: Serves as a critical intermediate or lead compound in pharmacological studies targeting vasodilation, calcium channel blockade, and anti-inflammatory pathways.
• Natural Product Chemistry: Employed in academic and industrial research for structure-activity relationship (SAR) studies and the synthesis of novel coumarin derivatives.
• Traditional Medicine Standardization: Acts as a marker compound for the standardization and authentication of herbal medicines derived from *Peucedanum* species.
• Dietary Supplement Formulation: Used in the development of high-end nutraceutical products focused on cardiovascular support.
• Preclinical Development: Utilized in *in vitro* and *in vivo* studies to evaluate pharmacokinetics, metabolism, and efficacy.

Basic Information

Product Name	Praeruptorin E
CAS No.	72463-77-5
Molecular Formula	C₂₁H₂₂O₇
Molecular Weight	386.40 g/mol
Synonyms	Pd-Ib; (+)-Praeruptorin E; 3'(S),4'(S)-Diisovalerylkhellactone; 3',4'-Di-O-isovalerylkhellactone; 3',4'-Diisovalerylkhellactone; cis-3',4'-Diisovalerylkhellactone; (3'S,4'S)-3',4'-Bis(3-methylbutanoyloxy)-3',4'-dihydroseselin
EINECS	Contact for details

Quality Control

Our Praeruptorin E is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (IR, NMR, MS) for structural confirmation, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.