Description

4-Hydroxyfenbendazole is a key metabolite and active pharmaceutical ingredient (API) of the broad-spectrum anthelmintic fenbendazole. This compound is critical for research and development in veterinary and human pharmacology, offering a pathway for studying drug metabolism and developing novel therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers, research institutions, and chemical suppliers focused on antiparasitic drug development and analytical reference standards.

Application

• Veterinary Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced antiparasitic formulations for livestock and companion animals.
• Metabolite Reference Standard: Used in analytical laboratories for drug metabolism studies, pharmacokinetic profiling, and bioanalytical method validation via HPLC or LC-MS.
• Research Chemical: Serves as a key reagent in biomedical research to investigate the mechanisms of benzimidazole anthelmintics and their metabolic pathways.
• Active Pharmaceutical Ingredient (API) Development: Employed in the R&D of new drug candidates targeting parasitic infections.
• Quality Control & Regulatory Testing: Essential for pharmaceutical QC labs to identify and quantify fenbendazole metabolites in final drug products and biological samples.

Basic Information

Product Name	4-Hydroxyfenbendazole
CAS No.	72447-64-4
Molecular Formula	C15H13N3O3S
Molecular Weight	315.35 g/mol
Synonyms	Fenbendazole Metabolite; Fenbendazole Hydroxide; [5-(Phenylsulfanyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester, 4-Hydroxy derivative; 4-Hydroxy Fenbendazole; 4-OH Fenbendazole; 4-HFBZ; Hydroxyfenbendazole; 4-Hydroxy methyl 5-(phenylthio)-2-benzimidazolecarbamate
EINECS	Contact for details

Quality Control

Our 4-Hydroxyfenbendazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-grade standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.