Description

1,6-Dihydro-1-Methyl-6-Oxo-n-Trimethylsilyl-3-Pyridinecarboxamide is a specialized organosilicon derivative of a pyridinecarboxamide, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the trimethylsilyl (TMS) protecting group, which offers enhanced stability and reactivity for precise chemical transformations. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly in medicinal chemistry research for developing new therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides, where its specific structure contributes to the final product's efficacy.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes for constructing heterocyclic compounds and other fine chemicals in R&D laboratories.
• Chemical Research & Development: Serves as a valuable reagent for method development and exploring new reaction pathways in academic and industrial settings.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or functional materials requiring silicon-containing moieties.

Basic Information

Product Name	1,6-Dihydro-1-Methyl-6-Oxo-n-Trimethylsilyl-3-Pyridinecarboxamide
CAS No.	72403-08-8
Molecular Formula	C11H18N2O2Si
Molecular Weight	238.36 g/mol
Synonyms	1-Methyl-6-oxo-1,6-dihydro-N-(trimethylsilyl)pyridine-3-carboxamide; N-(Trimethylsilyl)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide; 3-Pyridinecarboxamide, 1,6-dihydro-1-methyl-6-oxo-N-(trimethylsilyl)-; TMS-protected 1-methyl-6-oxo-1,6-dihydronicotinamide; Trimethylsilyl nicotinamide derivative
EINECS	Contact for details

Quality Control

Our 1,6-Dihydro-1-Methyl-6-Oxo-n-Trimethylsilyl-3-Pyridinecarboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.