Description

7-Iodo-1,2,3,4-Tetrahydroisoquinoline is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a valuable intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting neurological and cardiovascular disorders.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Heck) to introduce the tetrahydroisoquinoline scaffold into more complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core template for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Catalyst Development: Can be functionalized to create novel ligands for metal catalysis or as a component in organocatalysts.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, or plant growth regulators.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or advanced polymers.

Basic Information

Product Name	7-Iodo-1,2,3,4-Tetrahydroisoquinoline
CAS No.	72299-62-8
Molecular Formula	C9H10IN
Molecular Weight	259.09 g/mol
Synonyms	7-Iodo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-iodoisoquinoline; 7-Iodotetrahydroisoquinoline; Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-; 72299-62-8; 7-Iodo-THIQ
EINECS	Contact for details

Quality Control

Our 7-Iodo-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.