Description

4-(Hydroxymethyl)-1,2-o-Isopropylidene-3-o-Benzyl-β-L-Threo-Pentofuranose is a sophisticated, high-purity carbohydrate derivative and a crucial protected intermediate in organic synthesis. Its value lies in providing a chiral scaffold with orthogonal protecting groups, enabling precise and selective chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and nucleoside chemistry sectors, particularly for developing antiviral agents and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of nucleoside analogues and antiviral drugs.
• Nucleoside Chemistry: Used in the preparation of modified nucleosides and nucleotides for research and therapeutic applications.
• Carbohydrate Chemistry: Serves as a protected sugar derivative for complex oligosaccharide and glycoconjugate synthesis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and bioactive compounds.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring specific sugar moieties.

Basic Information

Product Name	4-(Hydroxymethyl)-1,2-o-Isopropylidene-3-o-Benzyl-β-L-Threo-Pentofuranose
CAS No.	72261-44-0
Molecular Formula	C16H22O6
Molecular Weight	310.34 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-benzyl-β-L-threo-pentofuranose; 3-O-Benzyl-1,2-O-isopropylidene-β-L-threo-pentofuranose; 3-O-Benzyl-1,2-O-isopropylidene-α-L-xylofuranose (related isomer); Benzyl-protected isopropylidene-L-threose derivative; L-Threose derivative, 3-O-benzyl-1,2-O-isopropylidene-; Protected L-threofuranose; 72261-44-0; NSC 406312
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ analytical techniques including HPLC, NMR, and IR spectroscopy to verify specifications, meeting the exacting standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.