Description

1-Bromo-2-Methyl-D3-Propane-3,3,3-D3 is a deuterium-labeled isotopologue of isobutyl bromide, a valuable building block in synthetic organic chemistry. This compound is specifically designed for use as an internal standard in mass spectrometry and as a tracer in metabolic and pharmacokinetic studies, ensuring high accuracy and reliability in analytical results. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise isotopic labeling for mechanistic studies, quantitative analysis, and the development of novel deuterated compounds.

Application

• Internal Standard for Mass Spectrometry (MS) and Gas Chromatography-Mass Spectrometry (GC-MS): Provides a stable, non-interfering reference for the accurate quantification of its non-deuterated counterpart in complex biological and chemical matrices.
• Metabolic Pathway Tracing: Used in pharmaceutical R&D to track the absorption, distribution, metabolism, and excretion (ADME) of drug candidates and bioactive molecules.
• Synthesis of Deuterated Compounds: Serves as a key alkylating agent for introducing deuterium-labeled isobutyl groups into target molecules, enhancing their stability and analytical properties.
• NMR Spectroscopy Studies: The deuterium atoms provide a silent background in 1H-NMR, simplifying spectral analysis for reaction monitoring and structural elucidation.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products during drug development and quality control.
• Agrochemical Research: Employed in environmental fate studies and metabolic profiling of pesticides and herbicides.

Basic Information

Product Name	1-Bromo-2-Methyl-D3-Propane-3,3,3-D3
CAS No.	72182-70-8
Molecular Formula	C4H6D3Br
Molecular Weight	152.03 g/mol (for C4H6D3Br)
Synonyms	Isobutyl-d3 bromide; 1-Bromo-2-methylpropane-3,3,3-d3; (2-Methylpropyl-d3) bromide; Deuterated isobutyl bromide; (CD3)2CDCH2Br; 2-Methyl-1-bromopropane-3,3,3-d3; tert-Butyl-d3 methyl bromide (common misnomer); Isobutyl-d3 bromide, 98 atom % D
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Methyl-D3-Propane-3,3,3-D3 is manufactured under strict quality protocols to ensure high isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % D), chemical purity by GC, and identity confirmation. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of analytical and pharmaceutical laboratories globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and organic solvent compatibility, ensure containers are kept in secondary containment and clearly labeled.

Specification

Item	Specification
Appearance	Clear Colorless to Pale Yellow Liquid
Identification (IR)	Conforms to Structure
Purity (GC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by NMR or MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.