Description

Methacetin-Methoxy-13C is a stable isotope-labeled analog of methacetin, where the methoxy group is enriched with carbon-13. This compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and precision in analytical measurements. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and diagnostic developers working on drug metabolism studies, clinical assays, and advanced bioanalytical method development.

Application

• Internal Standard for LC-MS/MS quantification of methacetin and its metabolites in biological matrices (plasma, serum, urine).
• Tracer compound in pharmacokinetic (PK) and drug metabolism studies.
• Critical reagent for the development and validation of high-throughput clinical diagnostic assays.
• Use in research investigating liver function and cytochrome P450 1A2 (CYP1A2) enzyme activity.
• Reference material for calibrating analytical instruments in forensic and anti-doping laboratories.
• Component in isotope dilution mass spectrometry (IDMS) for achieving definitive measurement results.

Basic Information

Product Name	Methacetin-Methoxy-13C
CAS No.	72156-70-8
Molecular Formula	C9H1113CNO2
Molecular Weight	166.19 g/mol (for 13C1 labeled form)
Synonyms	N-(4-Methoxyphenyl)acetamide-13C (methoxy); 4'-Methoxyacetanilide-13C (methoxy); 4-Acetamidoanisole-13C (methoxy); p-Acetanisidide-13C (methoxy); Methacetin-13C1 (O-methyl); [Methoxy-13C]Methacetin; 13C Labeled Methacetin; Isotopic Internal Standard Methacetin
EINECS	Contact for details

Quality Control

Every batch of Methacetin-Methoxy-13C is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support your regulatory filings, including isotopic enrichment (typically >99 atom % 13C) and chemical purity (typically >98% by HPLC). Certificates of Analysis (COA) detailing batch-specific results for identity, purity, and isotopic content are available upon request and are essential for GLP/GMP-compliant research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C. Keep the container sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (by 1H NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.