Description

3-Chloro-1-Phenylisoquinoline-4-Carbonitrile is a high-value, heterocyclic organic building block characterized by its fused isoquinoline core. This compound matters as a versatile synthetic intermediate, enabling the construction of complex molecular architectures for advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection and pest management.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: A valuable monomer or precursor for developing organic semiconductors, luminescent materials, or advanced polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes for studying biological processes.
• Academic & Contract Research: Essential for organic synthesis research in universities and contract research organizations (CROs).

Basic Information

Product Name	3-Chloro-1-Phenylisoquinoline-4-Carbonitrile
CAS No.	72118-85-5
Molecular Formula	C₁₆H₉ClN₂
Molecular Weight	264.71 g/mol
Synonyms	3-Chloro-1-phenyl-4-cyanoisoquinoline; 1-Phenyl-3-chloroisoquinoline-4-carbonitrile; 4-Cyano-3-chloro-1-phenylisoquinoline; 72118-85-5; 3-Chloro-1-phenylisoquinoline-4-carbonitrile; 1-Phenyl-3-chloro-4-cyanoisoquinoline; 3-Chloro-1-phenyl-4-isoquinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-1-Phenylisoquinoline-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.