Description

γ-Oxo-α,2-Bis[(trimethylsilyl)amino]benzenebutyric Acid Trimethylsilyl Ester is a sophisticated organosilicon compound featuring multiple trimethylsilyl protecting groups. This chemical is a critical advanced intermediate in organic synthesis, valued for its role in constructing complex molecular architectures where sensitive functional groups require protection. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis laboratories engaged in the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug candidates, particularly those requiring protected amino and carboxylic acid functionalities.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics, where the trimethylsilyl groups provide orthogonal protection strategies.
• Agrochemical Synthesis: Employed as a precursor in the development of advanced, high-performance crop protection agents and plant growth regulators.
• Material Science Precursor: Functions as a specialty monomer or intermediate in the synthesis of silicon-containing polymers and advanced organic materials.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis, enabling novel bond-forming reactions under mild conditions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on scale.

Basic Information

Product Name	γ-Oxo-α,2-Bis[(trimethylsilyl)amino]benzenebutyric Acid Trimethylsilyl Ester
CAS No.	72088-03-0
Molecular Formula	C22H42N2O2Si3
Molecular Weight	466.86 g/mol
Synonyms	Benzenebutanoic acid, γ-oxo-α,2-bis[(trimethylsilyl)amino]-, trimethylsilyl ester; 4-(2-Amino-5-[(trimethylsilyl)amino]phenyl)-4-oxobutanoic acid trimethylsilyl ester (bis-TMS derivative); γ-Oxo-α,2-bis(trimethylsilylamino)benzenebutanoic acid TMS ester; TMS-protected γ-keto amino acid derivative; Bis(trimethylsilyl)amino benzoyl butyrate TMS ester
EINECS	Contact for details

Quality Control

Every batch of γ-Oxo-α,2-Bis[(trimethylsilyl)amino]benzenebutyric Acid Trimethylsilyl Ester is manufactured and tested under a strict quality management system. We guarantee high purity and batch-to-batch consistency through comprehensive analytical protocols including NMR, HPLC, and GC-MS. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.