Description

(+)-Eptazocine CAS NO 72074-71-6 is a high-purity, enantiomerically pure benzomorphan derivative of significant interest in pharmaceutical research and development. This compound serves as a critical chiral intermediate and reference standard for the synthesis and analytical characterization of novel opioid receptor ligands. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in neuropharmacology and analgesic drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry Research: Serves as a key chiral building block or precursor for the synthesis of novel opioid analgesics with targeted receptor activity.
• Pharmacological Studies: Employed in in vitro and in vivo assays to study κ-opioid receptor (KOR) interactions, pain modulation pathways, and structure-activity relationships (SAR).
• Analytical Development: Critical for developing and calibrating chromatographic methods (HPLC, LC-MS) to separate and quantify enantiomers in complex matrices.
• Process Chemistry: Used in the development and optimization of asymmetric synthesis routes for complex pharmaceutical molecules.

Basic Information

Product Name	(+)-Eptazocine
CAS No.	72074-71-6
Molecular Formula	C15H21NO
Molecular Weight	231.33 g/mol
Synonyms	(+)-Eptazocine; (2R,6R,11R)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol; Eptazocine Hydrobromide (salt precursor); (2R,6R,11R)-6,11-Dimethyl-3-(3-methylbut-2-en-1-yl)-2,6-methano-1,2,3,4,5,6-hexahydro-3-benzazocin-8-ol; BRL-15723; Benzomorphan derivative
EINECS	Contact for details

Quality Control

Our (+)-Eptazocine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications for research use. Certificates of Analysis (COA) detailing results from HPLC, chiral analysis, NMR, and MS are provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.