Description

p-Toluenesulfonyloxyandrost-4-Ene-3,17-Dione-19-D2 is a high-purity, deuterated steroid derivative, specifically designed for advanced research and pharmaceutical development. This compound serves as a critical synthetic intermediate, offering enhanced metabolic stability and traceability in pharmacokinetic and metabolic studies due to its deuterium labeling. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on endocrinology, steroid chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Metabolic Tracer: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and quantify metabolic pathways using mass spectrometry.
• Reference Standard: Serves as an analytical standard for quality control and method validation in steroid analysis.
• Biochemical Research: Tool compound for investigating steroid hormone receptors, enzyme inhibition, and related biochemical pathways.
• Isotope-Labeled Synthesis: Enables the synthesis of more complex deuterated molecules for advanced research applications.

Basic Information

Product Name	p-Toluenesulfonyloxyandrost-4-Ene-3,17-Dione-19-D2
CAS No.	71995-65-8
Molecular Formula	C28H35D2O5S
Molecular Weight	487.66 g/mol (approx.)
Synonyms	19-Deuterio-17-oxoandrost-4-en-3-yl 4-methylbenzenesulfonate; Androst-4-ene-3,17-dione, 19-d2, 3-(p-toluenesulfonate); 19-D2-Androst-4-ene-3,17-dione 3-tosylate; Tosyloxyandrostenedione-19-d2; 3β-Tosyloxyandrost-4-ene-17-one-19-d2; Deuterated Androstenedione Tosylate; 71995-65-8
EINECS	Contact for details

Quality Control

Our p-Toluenesulfonyloxyandrost-4-Ene-3,17-Dione-19-D2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for isotopic enrichment (D-content). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.