Description

Bremazocine CAS NO 71990-00-6 is a potent and selective κ-opioid receptor (KOR) agonist, a key compound in advanced pharmacological research. Its high affinity and selectivity make it an indispensable tool for studying opioid receptor function, pain pathways, and neuropsychiatric disorders. This compound is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on neuroscience and analgesic drug discovery.

Application

• Neuroscience Research: A critical reference standard for investigating the role of κ-opioid receptors in the central nervous system.
• Analgesic Mechanism Studies: Used to explore non-addictive pathways for pain management and the development of novel analgesics.
• Psychiatric Disorder Models: Employed in preclinical research to study dysphoria, stress responses, and potential treatments for depression and addiction.
• Receptor Binding Assays: Serves as a high-affinity ligand in competitive binding experiments to characterize new chemical entities.
• Biochemical Pathway Analysis: A tool for elucidating downstream signaling cascades activated by KOR agonism.
• Reference Standard for QC: Used as an analytical standard in the quality control of related pharmaceutical compounds and research materials.

Basic Information

Product Name	Bremazocine
CAS No.	71990-00-6
Molecular Formula	C₂₅H₃₂N₂O₃
Molecular Weight	408.54 g/mol
Synonyms	(2S)-2-[(5R,6R,8R,9S)-9-Ethyl-8-(hydroxymethyl)-6,11-dimethyl-5,6,7,8,9,10-hexahydro-5,9-methanobenzocycloocten-3-yl]-7,8-dihydro-1H-4,6-ethenoisoquinolin-3(2H)-one; Bremazocine hydrochloride; 2-[(5R,6R,8R,9S)-9-Ethyl-8-(hydroxymethyl)-6,11-dimethyl-5,6,7,8,9,10-hexahydro-5,9-methanobenzocycloocten-3-yl]-4,5-epoxy-7,8-dihydro-3H-6-ethenoisoquinolin-3-one; C-16,903; BRN 3912823
EINECS	Contact for details

Quality Control

Our Bremazocine is manufactured under strict quality management systems to ensure the highest standards of purity and consistency for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines to support Good Laboratory Practice (GLP) and research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.