Description

1H-Indole-5-Carboxamidine is a high-purity, versatile chemical building block of significant interest in advanced organic synthesis. Its core value lies in its functional amidine group attached to the indole scaffold, making it a critical intermediate for constructing complex nitrogen-containing heterocycles. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors, receptor antagonists, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole structure.
• Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds and functionalized indole derivatives in medicinal chemistry.
• Biochemical Research: Employed as a research tool and standard in biochemical assays and studies involving enzyme inhibition or receptor binding.
• Material Science: Potential intermediate for synthesizing specialty polymers, dyes, or organic electronic materials.

Basic Information

Product Name	1H-Indole-5-Carboxamidine
CAS No.	71889-75-3
Molecular Formula	C9H9N3
Molecular Weight	159.19 g/mol
Synonyms	5-Carbamimidoyl-1H-indole; Indole-5-carboxamidine; 1H-Indole-5-carboximidamide; 5-Amidinoindole; 5-(Aminoiminomethyl)-1H-indole; 5-Carbamoylamidinoindole; 71889-75-3
EINECS	Contact for details

Quality Control

Our 1H-Indole-5-Carboxamidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.