Description

Avermectin A1A, 5-o-Demethyl-22,23-Dihydro- is a key semi-synthetic derivative of the naturally occurring avermectin family of macrocyclic lactones. This compound is highly significant as a crucial intermediate in the synthesis of more potent and selective endectocides and acaricides. It is primarily required by manufacturers in the agrochemical and pharmaceutical industries for research and production of next-generation parasitic control agents.

Application

• Agrochemical Intermediate: Primary use as a critical building block for synthesizing advanced generation avermectin-based pesticides and acaricides.
• Veterinary Pharmaceutical Research: Serves as a precursor in the development of novel antiparasitic drugs for livestock and companion animals.
• Crop Protection Product Development: Used in R&D for formulating new solutions against nematodes, mites, and insects in agriculture.
• Biochemical Research: Valuable reference standard and tool for studying the mode of action and metabolism of macrocyclic lactones.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the controlled synthesis of specialized pharmaceutical actives targeting parasites.

Basic Information

Product Name	Avermectin A1A, 5-o-Demethyl-22,23-Dihydro-
CAS No.	71827-03-7
Molecular Formula	C48H72O14
Molecular Weight	873.1 g/mol
Synonyms	5-O-Demethyl-22,23-dihydroavermectin A1a; 22,23-Dihydro-5-O-demethylavermectin A1a; 5-O-Desmethyl-22,23-dihydroavermectin A1a; Avermectin B1a, 5-O-demethyl-22,23-dihydro-; MK-0244; Ivermectin intermediate; Abamectin derivative; 5-O-Desmethyl-22,23-dihydroavermectin A1
EINECS	Contact for details

Quality Control

Our Avermectin A1A, 5-o-Demethyl-22,23-Dihydro- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for synthesis and research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.