Description

(3Z)-3-[(4-Iodophenyl)Imino]-1,3-Dihydro-2H-Indol-2-One is a specialized organic compound featuring an indolinone core substituted with a 4-iodophenylimino group, serving as a high-value synthetic intermediate. This compound matters for its role in facilitating complex molecular construction, particularly in the development of novel heterocyclic frameworks with potential biological activity. It is needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use in medicinal chemistry programs, catalyst ligand synthesis, and advanced material research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for constructing complex heterocyclic libraries for high-throughput screening.
• Agrochemical Development: Serves as a precursor in the design and synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes due to its distinctive structural motif.
• Organic Synthesis: Acts as a versatile intermediate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) leveraging the iodine substituent.
• Material Science Research: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its planar, conjugated structure.

Basic Information

Product Name	(3Z)-3-[(4-Iodophenyl)Imino]-1,3-Dihydro-2H-Indol-2-One
CAS No.	71824-67-4
Molecular Formula	C14H9IN2O
Molecular Weight	348.14 g/mol
Synonyms	3-[(4-Iodophenyl)imino]-1,3-dihydro-2H-indol-2-one; (Z)-3-((4-Iodophenyl)imino)indolin-2-one; 2H-Indol-2-one, 3-[(4-iodophenyl)imino]-1,3-dihydro-; Isatin 4-iodophenylimine; 71824-67-4; 3-(4-Iodophenylimino)indolin-2-one; (3Z)-3-[(4-Iodophenyl)imino]indolin-2-one
EINECS	Contact for details

Quality Control

Our (3Z)-3-[(4-Iodophenyl)Imino]-1,3-Dihydro-2H-Indol-2-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.