Description

1-[2-(Hydroxymethyl)Bicyclo[2.2.1]Hept-5-En-2-Yl]Ethan-1-One is a specialized bicyclic organic compound featuring both hydroxyl and ketone functional groups, making it a versatile chiral building block for advanced synthesis. Its unique norbornene-derived structure is valued for introducing rigidity and specific stereochemistry into target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Asymmetric Synthesis: Serves as a precursor or ligand in catalytic asymmetric reactions due to its rigid, three-dimensional scaffold.
• Polymer Chemistry: Used as a functional monomer or cross-linking agent for synthesizing specialty polymers with enhanced thermal and mechanical properties.
• Agrochemical Research: Employed in the synthesis of advanced, structurally complex pesticide and herbicide molecules.
• Material Science: Acts as a building block for liquid crystals, advanced resins, and other performance materials requiring specific molecular geometry.
• Flavor & Fragrance Industry: Potential intermediate for creating complex, musky, or woody aroma chemicals.

Basic Information

Product Name	1-[2-(Hydroxymethyl)Bicyclo[2.2.1]Hept-5-En-2-Yl]Ethan-1-One
CAS No.	71735-24-5
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	2-Acetyl-2-(hydroxymethyl)-5-norbornene; 5-Norbornene-2-methanol, 2-acetyl-; 2-(Hydroxymethyl)bicyclo[2.2.1]hept-5-en-2-yl methyl ketone; 2-Acetylmethyl-5-norbornene-2-methanol; Norbornene acetyl methanol derivative; Bicyclo[2.2.1]hept-5-ene-2-methanol, 2-acetyl-; (1R,2S,4R)-1-Acetyl-2-(hydroxymethyl)bicyclo[2.2.1]hept-5-ene (for specific enantiomer)
EINECS	Contact for details

Quality Control

Our 1-[2-(Hydroxymethyl)Bicyclo[2.2.1]Hept-5-En-2-Yl]Ethan-1-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.