Description

1-Bromo-11-Chloro-1-Undecyne is a high-purity, bifunctional alkyne building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive terminal alkyne and two distinct halogen handles (bromine and chlorine), makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as click chemistry, cross-coupling reactions, and polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly through Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, where its alkyne functionality enables modular compound library generation.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialized polymers, dendrimers, and functionalized surfaces via click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition).
• Ligand & Catalyst Development: Employed in the preparation of novel phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis and organometallic chemistry.
• Chemical Biology & Bioconjugation: Facilitates the site-specific labeling of proteins, peptides, and other biomolecules for diagnostic and therapeutic research.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex natural product analogs.

Basic Information

Product Name	1-Bromo-11-Chloro-1-Undecyne
CAS No.	71487-13-3
Molecular Formula	C11H18BrCl
Molecular Weight	265.62 g/mol
Synonyms	11-Chloro-1-bromo-1-undecyne; Undec-1-yn-1-yl Bromide, 11-Chloro Derivative; 1-Undecyne, 1-bromo-11-chloro-; Bromo(chloro)undecyne
EINECS	Contact for details

Quality Control

Our 1-Bromo-11-Chloro-1-Undecyne is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity (IR, NMR), purity (GC/HPLC), and impurity profiles. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.