Description

1-Bromo-8-Chloro-1-Octyne is a specialized halogenated alkyne building block of significant interest in advanced organic synthesis. Its unique bifunctional structure, featuring both bromo and chloro terminal groups separated by an alkyne linker, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions, click chemistry, and the synthesis of novel polymers or liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing halogenated alkynyl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides that require specific halogen-alkyne functionalities.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of advanced polymers, dendrimers, and liquid crystalline materials.
• Click Chemistry: The terminal alkyne group is amenable to copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and material surface functionalization.
• Organic Synthesis Building Block: Employed in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to create complex organic molecules.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and synthesizing novel chemical entities.

Basic Information

Product Name	1-Bromo-8-Chloro-1-Octyne
CAS No.	71487-12-2
Molecular Formula	C8H12BrCl
Molecular Weight	223.54 g/mol
Synonyms	8-Chloro-1-bromo-1-octyne; 1-Octyne, 1-bromo-8-chloro-; 1-Bromo-8-chloro-oct-1-yne; Bromochlorooctyne
EINECS	Contact for details

Quality Control

Our 1-Bromo-8-Chloro-1-Octyne is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.