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1,1-Bis(Trimethylsilyl)-3-Ethyl-2-Thiourea CAS NO 71456-98-9


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CAS No.:71456-98-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,1-Bis(Trimethylsilyl)-3-Ethyl-2-Thiourea is a specialized organosilicon-protected thiourea derivative, serving as a versatile reagent and intermediate in advanced organic synthesis. Its core value lies in its dual functionality, acting as both a silylating agent and a source of a protected thiocarbonyl group, which is crucial for constructing complex heterocycles and modifying sensitive molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity, moisture-sensitive building blocks.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing sulfur heterocycles or requiring silyl protection strategies.
  • Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the thiourea moiety is integral to biological activity.
  • Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and silicon-containing advanced materials.
  • Organic Synthesis Reagent: Employed as a sulfur transfer agent or for the introduction of the trimethylsilyl (TMS) group in multi-step synthetic sequences.
  • Chemical Research: A valuable tool in academic and industrial research laboratories for methodology development and exploring new reaction pathways.
  • Fine Chemical Production: Intermediate in the manufacture of complex fine chemicals, dyes, and photographic chemicals.

Basic Information

Item Detail
Product Name 1,1-Bis(Trimethylsilyl)-3-Ethyl-2-Thiourea
CAS No. 71456-98-9
Molecular Formula C9H24N2SSi2
Molecular Weight 248.55 g/mol
Synonyms N,N-Bis(trimethylsilyl)-N'-ethylthiourea; 3-Ethyl-1,1-bis(trimethylsilyl)-2-thiourea; 1,1-Bis(trimethylsilyl)-3-ethylthiourea; BTSETU; Ethyl(trimethylsilyl)thiocarbamate trimethylsilyl ester; Thiourea, N,N-bis(trimethylsilyl)-N'-ethyl-; TMS-protected ethyl thiourea
EINECS Contact for details

Quality Control

Our 1,1-Bis(Trimethylsilyl)-3-Ethyl-2-Thiourea is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques including NMR, HPLC, and GC to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Purity (GC) ≥ 98.0%
Melting Point Contact for details
Heavy Metals < 20 ppm
Residual Solvents (GC) Meets ICH guidelines
Water Content (KF) < 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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