Description

4-Methylphenyldithiocarbamic Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring a dithiocarbamate functional group. This compound is valued as a key synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for the controlled introduction of sulfur-containing moieties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, especially those containing thiourea or dithiocarbamate pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where the dithiocarbamate group imparts specific biological activity.
• Ligand Precursor: Acts as a precursor for the preparation of dithiocarbamate ligands used in coordination chemistry and catalysis.
• Polymer Modification: Employed in the functionalization of polymers to introduce specific chemical handles or alter material properties.
• Protecting Group Chemistry: The trimethylsilyl (TMS) group can act as a protecting group for the dithiocarbamic acid functionality during multi-step syntheses.
• Organic Synthesis Reagent: Facilitates various carbon-sulfur bond-forming reactions and serves as a sulfur transfer agent in laboratory-scale preparations.

Basic Information

Product Name	4-Methylphenyldithiocarbamic Acid Trimethylsilyl Ester
CAS No.	71456-95-6
Molecular Formula	C11H17NOSSi
Molecular Weight	239.41 g/mol
Synonyms	p-Tolyldithiocarbamic Acid Trimethylsilyl Ester; Trimethylsilyl p-Tolyldithiocarbamate; N-(Trimethylsilyl)-S-(4-methylphenyl)carbamothioate; 4-Methylphenylcarbamodithioic Acid Trimethylsilyl Ester; (4-Methylphenyl)(trimethylsilyl)dithiocarbamate; TMS-p-Tolyldithiocarbamate; CAS 71456-95-6
EINECS	Contact for details

Quality Control

Our production of 4-Methylphenyldithiocarbamic Acid Trimethylsilyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.