Description

Silychristin(P) CAS NO 71328-57-9 is a specific stereoisomer of silychristin, a bioactive flavonolignan primarily derived from the milk thistle plant (*Silybum marianum*). This compound is of significant interest for its role as a key analytical reference standard and a potential precursor in high-value phytopharmaceutical research and development. It is essential for organizations in the nutraceutical, pharmaceutical, and analytical chemistry sectors requiring precise, high-purity materials for quality control, method validation, and bioactive compound studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of silymarin and milk thistle extracts in pharmacopoeial methods (e.g., USP, EP).
• Nutraceutical R&D: Serves as a critical standard in the research and quality control of dietary supplements containing milk thistle, ensuring product potency and authenticity.
• Bioactivity Studies: Employed in preclinical research to investigate the specific pharmacological properties, metabolic pathways, and structure-activity relationships of silychristin isomers.
• Analytical Method Development: Essential for developing and validating robust HPLC, UPLC, and LC-MS/MS methods for the separation and quantification of complex flavonolignan mixtures.
• Phytochemical Isolation & Purification: Acts as a benchmark for the isolation and purification of silychristin and related compounds from natural sources or synthetic processes.
• Cosmeceutical Ingredient Research: Utilized in studies exploring the antioxidant and skin-protective benefits of milk thistle-derived compounds for cosmetic formulations.

Basic Information

Item	Details
Product Name	Silychristin(P)
CAS No.	71328-57-9
Molecular Formula	C25H22O10
Molecular Weight	482.44 g/mol
Synonyms	Silychristin P; (2R,3R)-3,5,7-Trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one; 2,3-Dehydrosilychristin; Silychristin B; Isosilychristin; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Silychristin(P) is produced and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring compliance with the stringent requirements for reference standards. Our quality protocols are designed to meet the needs of pharmaceutical and analytical laboratories, with testing performed using validated methods such as HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.