Description

Thiazolidine-4-Carboxylic Acid Di(Trimethylsilyl) Derivative is a key silylated derivative of the naturally occurring amino acid derivative, thiazolidine-4-carboxylic acid. This compound is primarily valued as a versatile protected intermediate and synthetic building block in advanced organic synthesis, particularly for peptide and heterocyclic chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, specialized reagents for complex molecule construction.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those containing thiazolidine or proline-like scaffolds for metabolic and neurological targets.
• Peptide Chemistry: Serves as a protected form of thiazolidine-4-carboxylic acid for the incorporation of modified amino acids into peptides, influencing structure and bioactivity.
• Ligand and Catalyst Synthesis: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators with heterocyclic cores.
• Chemical Biology Probes: Utilized to create labeled or tagged compounds for studying biological pathways and enzyme mechanisms.
• Material Science: Investigated as a monomer or additive for specialized polymers and coatings.

Basic Information

Product Name	Thiazolidine-4-Carboxylic Acid Di(Trimethylsilyl) Derivative
CAS No.	71240-84-1
Molecular Formula	C10H23NO2SSi2
Molecular Weight	277.53 g/mol
Synonyms	Thiazolidine-4-carboxylic acid, bis(trimethylsilyl) ester; 4-Thiazolidinecarboxylic acid, bis(trimethylsilyl) derivative; Timonacic acid bis(trimethylsilyl) ester; L-Thiazolidine-4-carboxylic acid di-TMS; TCA Di-TMS; Bis(trimethylsilyl) thiazolidine-4-carboxylate; 2,2,5,5-Tetramethyl-4-thia-2,5-disila-1-azacyclopentane-3-carboxylic acid (derivative)
EINECS	Contact for details

Quality Control

Our Thiazolidine-4-Carboxylic Acid Di(Trimethylsilyl) Derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in GMP-oriented research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.