Description

[(2,3-Dihydro-2-Methyl-1,3-Dioxo-1H-Isoindol)-4-Yl]Methylcarbamic Acid Chloride is a specialized, high-purity chemical intermediate designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring a reactive building block to introduce the N-methylcarbamoyl chloride moiety into complex molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing isoindoline-1,3-dione (phthalimide) structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its reactive acid chloride group facilitates amide bond formation.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or functional group in the design of peptide analogs and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Material Science Research: Employed in the development of novel polymers and functional materials that require the incorporation of specific, chemically defined side chains.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	[(2,3-Dihydro-2-Methyl-1,3-Dioxo-1H-Isoindol)-4-Yl]Methylcarbamic Acid Chloride
CAS No.	71173-81-4
Molecular Formula	C11H9ClN2O3
Molecular Weight	252.65 g/mol
Synonyms	4-[(Chlorocarbonyl)(methyl)amino]-2-methyl-1H-isoindole-1,3(2H)-dione; N-Methyl-N-[(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)]carbamoyl chloride; 4-(N-Methylcarbamoyloxy)phthalimide Chloride; Methylcarbamic acid, N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)-, chloride; 71173-81-4; 4-Isocyanato-2-methylphthalimide derivative
EINECS	Contact for details

Quality Control

Our [(2,3-Dihydro-2-Methyl-1,3-Dioxo-1H-Isoindol)-4-Yl]Methylcarbamic Acid Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.