Description

(4R,4'S)-2,2'-Diphenyl-4,4'-Bi[1,3,2-Dioxaborolane] is a high-purity, chiral bis-boronate ester compound, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile and stereochemically defined coupling partner for Suzuki-Miyaura cross-coupling reactions, enabling the construction of complex, optically active molecules. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the development of stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a starting material for creating novel chiral ligands and organometallic catalysts for asymmetric catalysis.
• Advanced Material Research: Employed in the construction of chiral polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in stereochemical studies and drug discovery.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and total synthesis projects.

Basic Information

Item	Detail
Product Name	(4R,4'S)-2,2'-Diphenyl-4,4'-Bi[1,3,2-Dioxaborolane]
CAS No.	71166-92-2
Molecular Formula	C18H18B2O4
Molecular Weight	327.96 g/mol
Synonyms	(4R,4'S)-2,2'-Diphenyl-4,4',5,5'-tetrahydro-4,4'-bi-1,3,2-dioxaborole; (R,R)-2,2'-Diphenyl-4,4',5,5'-tetrahydro-[4,4']bi[[1,3,2]dioxaborolanyl]; Chiral Bis(pinacol boronate); (R,R)-Bis(pinacolatodiboron); (4R,4'S)-Diphenyl-4,4'-bi-1,3,2-dioxaborolane; (R,R)-DPB; (R,R)-2,2'-Diphenyl-4,4'-bi(1,3,2-dioxaborolane)
EINECS	Contact for details

Quality Control

Our (4R,4'S)-2,2'-Diphenyl-4,4'-Bi[1,3,2-Dioxaborolane] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.