Description

3-Thiophenecarboxylic Acid, 2-Fluoro- is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role in introducing both a carboxylic acid and a fluorine substituent onto a thiophene scaffold, enabling precise molecular modifications. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated thiophene moiety.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its conjugated system.
• Chemical Synthesis: Employed as a versatile building block in cross-coupling reactions, esterifications, and amide bond formations to create complex molecular architectures.
• Fluorine Chemistry Studies: Utilized in academic and industrial R&D to study the effects of fluorine substitution on the properties and reactivity of heterocyclic compounds.

Basic Information

Product Name	3-Thiophenecarboxylic Acid, 2-Fluoro-
CAS No.	71154-31-9
Molecular Formula	C5H3FO2S
Molecular Weight	146.14 g/mol
Synonyms	2-Fluoro-3-thiophenecarboxylic acid; 2-Fluorothiophene-3-carboxylic acid; 3-Carboxy-2-fluorothiophene; 2-Fluoro-3-thenoic acid; 2-Fluorothiophene-3-carboxylate; 2-Fluoro-3-thiophenecarboxylate; 2-Fluoro-3-thiophene carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxylic Acid, 2-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.