Description

2-[2-Hydroxy-3-[2-(Indol-3-Yl)-1,1-Dimethylethylamino]Propoxy]Benzonitrile is a high-purity, complex organic compound featuring a unique molecular architecture that combines indole and benzonitrile moieties. This structure is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents. The compound's specific properties make it a valuable building block for exploring new chemical entities in medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies to develop new molecules with optimized biological activity.
• Biochemical Research: Employed in laboratory settings to study enzyme inhibition, receptor binding, or other specific biochemical interactions.
• Fine Chemical Synthesis: Acts as a specialized intermediate for producing complex, high-value organic compounds for various advanced applications.

Basic Information

Product Name	2-[2-Hydroxy-3-[2-(Indol-3-Yl)-1,1-Dimethylethylamino]Propoxy]Benzonitrile
CAS No.	71119-11-4
Molecular Formula	C22H25N3O2
Molecular Weight	363.46 g/mol
Synonyms	Nadolol Impurity; 1-(tert-Butylamino)-3-[(5-cyano-2-hydroxyphenoxy)]-2-propanol Indole Analog; 2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-(1H-indol-3-yl)benzonitrile; 5-Cyano-2-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl Indole; Nadolol Related Compound; CAS 71119-11-4
EINECS	Contact for details

Quality Control

Our 2-[2-Hydroxy-3-[2-(Indol-3-Yl)-1,1-Dimethylethylamino]Propoxy]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.