Description

2,4-Diaminotoluene-Alpha,Alpha,α-D3 is a deuterated isotopologue of 2,4-diaminotoluene, where three hydrogen atoms are replaced with deuterium at the methyl group. This compound is a critical stable isotope-labeled standard used for precise quantitative analysis and metabolic studies, ensuring high accuracy in mass spectrometry by eliminating interference from the unlabeled compound. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors who require definitive internal standards for method development and regulatory compliance.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial reference compound in LC-MS and GC-MS analysis for the accurate quantification of 2,4-diaminotoluene and related metabolites.
• Pharmaceutical Research & Metabolism Studies: Used in pharmacokinetic and drug metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of compounds.
• Environmental and Industrial Hygiene Monitoring: Employed as a standard in methods analyzing occupational exposure to toluene diamines or monitoring environmental samples.
• Dye and Polymer Chemistry Research: Acts as a labeled precursor in mechanistic studies of dye synthesis and polymer curing processes.
• Regulatory Compliance & Method Validation: Supports the development and validation of analytical methods to meet stringent FDA, EPA, and ICH guidelines.
• Isotope Dilution Analysis: Fundamental for high-precision isotope dilution techniques in analytical chemistry.

Basic Information

Product Name	2,4-Diaminotoluene-Alpha,Alpha,α-D3
CAS No.	71111-08-5
Molecular Formula	C7H7D3N2
Molecular Weight	125.18 g/mol
Synonyms	2,4-Diaminotoluene-d3; 2,4-Toluenediamine-d3; 2,4-Diamino-1-methylbenzene-d3; 4-Methyl-1,3-benzenediamine-d3; Deuteron 2,4-DAT; Toluene-2,4-diamine-d3; 2,4-Diaminotoluene (methyl-d3); 1-Methyl-2,4-diaminobenzene-d3
EINECS	Contact for details

Quality Control

Our 2,4-Diaminotoluene-Alpha,Alpha,α-D3 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D-content), chemical purity by HPLC, and identity confirmation. We adhere to cGMP principles for consistent production, and our quality protocols are designed to support your regulatory submissions and method validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.