Description

Bicyclo[2.1.1]Hexane-2-Carboxylic Acid, 2-Amino- (9Ci) is a specialized, high-value bicyclic amino acid derivative characterized by its unique strained ring structure. This compound matters as a sophisticated building block in advanced organic synthesis, offering a rigid, three-dimensional scaffold that is crucial for modulating the physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, particularly in the design of novel active ingredients and peptidomimetics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry: Used to introduce conformational constraint into peptide backbones, enhancing metabolic stability and receptor selectivity in drug discovery programs.
• Agrochemical Research: Employed in the development of new herbicides and pesticides with unique modes of action derived from its bicyclic framework.
• Ligand Synthesis: Acts as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers with specific mechanical or optical properties.
• Chemical Biology: Utilized as a probe or tag to study protein-protein interactions and enzyme mechanisms.

Basic Information

Product Name	Bicyclo[2.1.1]Hexane-2-Carboxylic Acid, 2-Amino- (9Ci)
CAS No.	71046-30-5
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	2-Aminobicyclo[2.1.1]hexane-2-carboxylic acid; 2-Amino-2-bicyclo[2.1.1]hexanecarboxylic acid; (1S,2R,4S)-2-Aminobicyclo[2.1.1]hexane-2-carboxylic acid; Bicyclo[2.1.1]hexane-2-carboxylic acid, 2-amino-; 2-Azabicyclo[2.1.1]hexane-3-carboxylic acid derivative; BCHCA; ABHCA; 71046-30-5
EINECS	Contact for details

Quality Control

Our Bicyclo[2.1.1]Hexane-2-Carboxylic Acid, 2-Amino- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.