Description

S-(-)-Nicotine-D1'-(5')-Iminium Diperchlorate Salt is a high-purity, isotopically labeled derivative of nicotine, specifically designed for advanced research and analytical applications. This compound serves as a critical reference standard and precursor in the study of nicotine metabolism, pharmacokinetics, and receptor interactions. It is essential for researchers and developers in the pharmaceutical, analytical chemistry, and life science sectors who require precise tools for method development, quantification, and mechanistic studies.

Application

• Primary use as a high-purity Internal Standard (IS) or Reference Standard for mass spectrometry (LC-MS/MS, GC-MS) in bioanalytical method development and validation.
• Critical reagent in metabolic pathway studies and pharmacokinetic research of nicotine and related alkaloids.
• Precursor for the synthesis of other labeled nicotine analogs and metabolites for tracer studies.
• Used in forensic and clinical toxicology laboratories for the accurate quantification of nicotine and its derivatives in complex biological matrices.
• Tool compound in neuropharmacology research for investigating nicotinic acetylcholine receptor (nAChR) binding and function.
• Component in the development and calibration of diagnostic assays and testing kits.

Basic Information

Product Name	S-(-)-Nicotine-D1'-(5')-Iminium Diperchlorate Salt
CAS No.	71014-67-0
Molecular Formula	C₁₀H₁₃DN₂·2ClO₄
Molecular Weight	Contact for details
Synonyms	(S)-Nicotine-D1'-(5')-Iminium Diperchlorate; (S)-Nicotine-5'-d1 Iminium Diperchlorate; Deuterated Nicotine Iminium Salt; Nicotine-d1 Iminium Perchlorate; S-Nicotine-5'-d1 Iminium Diperchlorate; 1-Methyl-2-(3-pyridyl)pyrrolidine-5'-d1 Iminium Diperchlorate; (2'S)-1-Methyl-2-(3-pyridinyl)-2-pyrrolidinyl-5'-d1-methaniminium Diperchlorate
EINECS	Contact for details

Quality Control

Every batch of S-(-)-Nicotine-D1'-(5')-Iminium Diperchlorate Salt is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing comprehensive analytical results, including isotopic purity and chemical purity by HPLC, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong oxidizing nature, the container must be kept tightly sealed in a dry environment and stored separately from incompatible materials such as reducing agents, organic compounds, and combustible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.