Description

4-(p-Chlorophenyl)-2-(1,3-Dioxo-1H-Isoindol-2-Yl)-5-Thiazoleacetic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block with a fused heterocyclic structure. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing new therapeutic agents, particularly in areas requiring specialized thiazole and isoindole motifs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial research.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	4-(p-Chlorophenyl)-2-(1,3-Dioxo-1H-Isoindol-2-Yl)-5-Thiazoleacetic Acid Methyl Ester
CAS No.	71013-48-4
Molecular Formula	C20H13ClN2O4S
Molecular Weight	412.85 g/mol
Synonyms	Methyl 4-(4-chlorophenyl)-2-(1,3-dioxoisoindolin-2-yl)-1,3-thiazole-5-acetate; 2-[4-(4-Chlorophenyl)-5-(2-methoxy-2-oxoethyl)-1,3-thiazol-2-yl]isoindoline-1,3-dione; 4-(4-Chlorophenyl)-2-(1,3-dioxo-1H-isoindol-2-yl)-5-thiazoleacetic acid methyl ester; 4-(p-Chlorophenyl)-2-(1,3-dioxo-1H-isoindol-2-yl)-5-thiazoleacetic acid methyl ester; 71013-48-4; 4-(4-Chlorophenyl)-2-(1,3-dioxoisoindolin-2-yl)-1,3-thiazole-5-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-(p-Chlorophenyl)-2-(1,3-Dioxo-1H-Isoindol-2-Yl)-5-Thiazoleacetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.