Description

(3Aβ,7Aβ)-Octahydro-2β-Phenylthio-1α,3α-Methano-1H-Indene is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its complex, rigid bicyclic framework and the presence of a sulfur-containing functional group, which makes it a versatile precursor for constructing pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring stereochemically defined scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targets.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce complex molecular architecture into target compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for drug discovery programs.
• Catalyst and Ligand Development: Acts as a precursor for synthesizing novel chiral ligands or organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Used in the multi-step synthesis of high-value, low-volume specialty chemicals for agrochemical or material science applications.
• Academic Research: A valuable compound for methodological studies in organic chemistry, particularly those exploring new C-S bond formation or rearrangements on polycyclic systems.

Basic Information

Product Name	(3Aβ,7Aβ)-Octahydro-2β-Phenylthio-1α,3α-Methano-1H-Indene
CAS No.	70938-93-1
Molecular Formula	C16H20S
Molecular Weight	244.40 g/mol
Synonyms	2β-(Phenylthio)-1α,3α-methano-1H-indene, octahydro-; 2-Phenylthio-octahydro-1,3-methano-1H-indene; (1S,2R,3S,4R,7S)-2-(Phenylthio)tricyclo[2.2.1.03,7]heptane; (1R,2S,3R,4S,7R)-2-(Phenylthio)tricyclo[2.2.1.03,7]heptane; Phenylthio-substituted norbornane derivative; Bicyclo[2.2.1]heptane, 2-(phenylthio)-, (1S,2R,3S,4R,7S)-rel-
EINECS	Contact for details

Quality Control

Our (3Aβ,7Aβ)-Octahydro-2β-Phenylthio-1α,3α-Methano-1H-Indene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; prolonged exposure to air should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.