Description

Ethyl-2,2,2-D3-Malonic Acid is a deuterated derivative of malonic acid diethyl ester, specifically labeled on the ethyl ester moiety. This compound is a crucial stable isotope-labeled building block, enabling advanced research and development in analytical chemistry and life sciences. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical instrumentation industries for applications such as internal standards, tracer studies, and metabolic pathway analysis.

Application

• Deuterated Internal Standard for Mass Spectrometry (MS): Essential for quantitative analysis in LC-MS and GC-MS methods, providing high accuracy and precision in pharmacokinetic and bioanalytical studies.
• Synthetic Intermediate for Labeled Compounds: Serves as a key precursor in the synthesis of more complex deuterium-labeled pharmaceuticals, agrochemicals, and organic materials.
• Metabolic Research & Tracer Studies: Used to investigate drug metabolism, biochemical pathways, and environmental fate of chemicals without isotopic interference.
• NMR Spectroscopy Solvent & Reagent: Employed in nuclear magnetic resonance (NMR) spectroscopy as a reagent or in deuterated solvent systems for structural elucidation.
• Organic Electronics & Material Science: Acts as a specialized monomer or modifying agent in the development of novel organic semiconductors and polymers.

Basic Information

Product Name	Ethyl-2,2,2-D3-Malonic Acid
CAS No.	70907-93-6
Molecular Formula	C7H7D3O4
Molecular Weight	161.17 g/mol
Synonyms	Diethyl (2,2,2-D3)malonate; Diethyl-d3 Malonate; Malonic Acid-d3 Diethyl Ester; Diethyl Malonate-d3; Ethyl-d3 Malonate; Diethyl (2,2,2-trideuterio)propanedioate; Propanedioic acid, diethyl-d3 ester; Diethyl 2,2,2-trideuteriomalonate
EINECS	Contact for details

Quality Control

Our Ethyl-2,2,2-D3-Malonic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, GC-MS, and HPLC to verify chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.