Description

Nafimidone CAS NO 70891-37-1 is a specialized organic compound belonging to the imidazolidinone class. This chemical is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key synthetic intermediate or a pharmacologically active scaffold. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents. The compound's specific structure makes it a valuable building block for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially in central nervous system (CNS) targeted research.
• Medicinal Chemistry Research: Used as a core scaffold or a functionalized fragment in structure-activity relationship (SAR) studies to optimize biological potency and selectivity.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and validate novel therapeutic targets.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling in related pharmaceutical processes.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and custom synthesis manufacturers to produce tailored molecules for client projects.

Basic Information

Product Name	Nafimidone
CAS No.	70891-37-1
Molecular Formula	C15H14N2O2
Molecular Weight	254.29 g/mol
Synonyms	Nafimidone; 1-(2-Naphthyl)-2-propylimidazolidin-4-one; 1-Naphthalen-2-yl-2-propylimidazolidin-4-one; 1-(Naphthalen-2-yl)-2-propylimidazolidin-4-one; Nafimidona; Nafimidonum; GYKI-33,343
EINECS	Contact for details

Quality Control

Every batch of Nafimidone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency of the material meets the exacting requirements of research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay purity and impurity profiles. Our quality protocols are designed to support regulatory filings and ensure reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.