Description

8-Chloroisoquinoline 2-Oxide is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and catalysis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the research and development of organic electronic materials and fluorescent dyes.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including cyclization and functionalization reactions.

Basic Information

Product Name	8-Chloroisoquinoline 2-Oxide
CAS No.	70810-27-4
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	8-Chloro-2-isoquinolinol 1-oxide; 8-Chloro-1-hydroxyisoquinoline; 8-Chloroisoquinoline N-oxide; Isoquinoline, 8-chloro-, 2-oxide; 8-Chloro-2-isoquinolinone 1-oxide; 8-Chloro-1-isoquinolinol N-oxide
EINECS	Contact for details

Quality Control

Our 8-Chloroisoquinoline 2-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure during handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.